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Definition
The myocardial infarction (heart attack) preferentially occurs when the heart arteries present plaque of atherosclerosiss ofatheroma reducing the blood output. Much more rarely, the myocardial infarction is secondary to a reduction of the diameter of the heart artery, due to its contraction, without any pre-existing lesion. The destruction of the cardiac muscle evolves from in- to outward the heart and from the centre of the necrosis toward the periphery. 50% of the area, which is no longer supplied in oxygen, is destroyed within 2 hours, 100% within 4 to 6 hours. This rate varies from an individual to the other. The deterioration of the heart contractile function is always associated to a myocardial infarction, whose healthy part of the muscle contracts more than usually. If 25% of the cardiac muscle is affected, the left cardiac failure occurs; if more than 40% of the heart muscle is affected, death is ineluctable in the absence of an emergency new vascularisation. File last modified on july 24, 2006 |
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